Furthermore, through immunohistochemical analysis, we found that normal duct epithelium expressed GLI1 predominantly in the nucleus along with TSHZ2 and CtBP2: breast cancer cells, which did not express TSHZ2 but CtBP2, exhibited the increase in the expression of AEBP1 and CXCR4 and also in the cytoplasmic distribution of GLI1. This evidence concerns the gene GLI1 and breast carcinoma.