MYH11 is the proposed candidate gene at this interval as defects in this gene underlie aortic aneurysm familial thoracic type 4 (AAT4) [MIM: 132900] and also contribute to familial thoracic aortic aneurysm and dissection (TAAD) and patent arterial duct (PDA). The gene discussed is MYH11; the disease is thoracic aortic aneurysm.