TBX1 and coronary artery disorder: These CNVs comprised mostly subtelomeric or centromeric imbalances and distributed on chromosomes such as 2p, 2q, 3p, 4q, 6p, 15q, 16q, 21q and 22q and most of these CNVs located on chromosomes 2, 3, 4, 7, 16 and X. The CNVs sizes identified in our VSD study are much smaller than those deposited in CHD wiki, which reports three regions (4q-ter, 15q26.2, 16q22) and one gene (TBX1) related to CHD.