HLA-C and Autoimmunity: Genes coding for class I and II major histocompatibility molecules (MHC) were also found in the group 2 network, highlighting the role of HLA-G (MHC class I) for protecting renal transplants from autoimmunity [33] and the function of Hla-dpb1 (MHC class II) in renal allograft rejection [34].