Univariate Cox regression analysis identified 20 potential predictors of mortality (Table 4), including sex, smoking, BMI, AKI, shock on admission, score of the Glasgow coma scale, mean arterial pressure, pulse and respiratory rates, serum albumin levels, AST, alanine aminotransferase, BUN, creatinine, hemoglobin, white blood cell count, APACHE II score, SOFA score, RIFLE score, and D1-UE-Cd. The gene discussed is ALB; the disease is acute kidney injury.