APOBEC3G and AIDS: Most studies on vaccine development and host-pathogen interaction that have been carried out extensively in the western world, for the development of new antiretroviral therapies are mostly based on subtype B. Recently, efforts have been focused on the host genetic factors that affect disease progression in HIV-1/AIDS [8,9] such as DC-SIGN, CCR5, SAMHD1 and APOBEC3G.