The SNPs in PNPLA3 and SAMM50 (OMIM # 612058) (rs738409, rs2896019; NM_025225.2:c.979+542T>G, rs3761472; NM_015380.4:c.329A>G) were previously identified in GWAS studies and generally had increased frequencies in the NAFLD population compared with our controls, the sample Bronx population, and expected population frequencies. The gene discussed is SAMM50; the disease is metabolic dysfunction-associated steatotic liver disease.