Common SNP variations in an intron of CHUK (OMIM # 600664) (rs11597086; (NM_001278.3:c.1974+36T>G)) and exon of ERLIN1 (OMIM # 611604) (rs2862954; (NM_001100626.1:c.871A>G)) occurred less frequently in both the NAFLD cases and the sample Bronx population than would be expected in a random Puerto Rican population. The gene discussed is ERLIN1; the disease is metabolic dysfunction-associated steatotic liver disease.