However, a robust association is present only in gastric MALT lymphoma with Helicobacter pylori (Hp), where 90% of cases are Hp+.7 Moreover, Hp eradication therapy is effective in gastric MALT Hp+ lymphoma with a remission rate around 80%8,9 and also long-term results are excellent.10 The studies on Hp and gastric MALT lymphoma have profoundly influenced our understanding of the pathogenesis of lymphomas and modified our management, because, for the first time in the history of medical oncology, cancer has been cured by antibiotic therapy. The gene discussed is HP; the disease is cancer.