For example, in the New York–based study of over 2000 older adults (mean age of 77.2 y) the middle and the highest tertiles of a DP that negatively correlated to red or organ meats and butter and positively correlated to fish, nuts, fruits, and cruciferous/green leafy vegetables were associated with 19% and 38% decreased risk of AD compared to the lowest tertile over 4 y and were not attenuated by apoE ε4 status (19). This evidence concerns the gene APOE and Alzheimer disease.