NFKB1 and diffuse large B-cell lymphoma: Finally, to verify that iNUB decreased viability of ABC-DLBCL by acting upstream of IKKβ, we lentivirally reconstituted HBL-1 cells with a constitutively active IKKβ (caIKKβ) mutant that drives canonical NF-κB signaling independent of upstream events34.