NF-κB is necessary for maintenance of high expression level of anti-apoptotic and pro-inflammatory factors in ABC-DLBCL, and therefore we evaluated by qPCR the relative mRNA expression levels of a panel of NF-κB target genes (c-FLIP, BclXL, TNFAIP3/A20, TNFα, NFKBIA/IκBα, IL-6, IL-10 and JunB) in the ABC-DLBCL cell lines HBL-1, OCI-Ly3, TMD8 and RIVA (Fig. 7a). The gene discussed is TNF; the disease is diffuse large B-cell lymphoma.