In non-T2D, the CLOCK SNP was no associated neither with stroke (HR: 1.59; 95 % CI 0.83–3–08; P = 0.165 nor with myocardial infarction (HR: 0.95; 95 % CI 0.48–1.89; P = 0.906). Here, CLOCK is linked to myocardial infarction.