ANGPTL8 and diabetes mellitus: As shown by Spearman’s correlation, serum betatrophin level in all individuals was positively and significantly correlated with duration of DM (r = 0.385, P < 0.001), SBP (r = 0.194, P = 0.032), BMI (r = 0.194, P = 0.031), FBG (r = 0.175, P = 0.048), ACR (r = 0.427, P < 0.001), HbA1C (%) (r = 0.264, P = 0.003), and triglycerides (r = 0.282, P = 0.001) (Table 2).