ANGPTL3 and coronary artery disorder: Using comparative analysis of genome-wide association studies, Angelakopoulou et al. demonstrated that a single nucleotide polymorphism of ANGPTL3 (rs12042319) was associated with coronary heart disease risk (OR = 1.11; 95 % CI = 1.03 ~ 1.19), total cholesterol, LDL-cholesterol, TG, and interleukin-6 [33].