According to the data for the rs53576 polymorphism of the OXTR gene in 12 nations, the nations with higher frequency of A allele (Japan, China, Korea) are more collectivistic in comparison with those having higher frequency of G allele (USA, UK, Australia, Canada, Netherlands, Italy, Sweden, Germany, Finland) but at the same time the last ones seem to be more predisposed to major depressive disorder [17]. Here, OXTR is linked to major depressive disorder.