CDK4 and gastric cancer: Although previous studies have shown that RASSF1A can function as a tumour suppressor gene by interacting with DNA repair proteins[30, 36], we showed that RASSF1A could inhibit the growth of gastric cancer cells by upregulating the expression of miR-711, which arrests gastric cancer cells in the G1 phase of the cell cycle by downregulating the expression of CDK4.