After adjusting for above significant covariates, CRC patients, particularly those with colon cancer carrying the TT genotype of RAD52 rs11226, displayed a longer survival in a recessive model (HR 0.70; 95% CI 0.52–0.93; p = 0.02 and HR 0.60; 95% CI 0.41–0.89; p = 0.01, respectively; Supplementary Table 4). Here, RAD52 is linked to colorectal carcinoma.