Using transcription factor binding site (TFBS) data identified by ChIP-seq in a lung adenocarcinoma cell line (A549) we quantified binding sites for nine transcription factors Ctcf (GSM803456), Bcl3 (GSM1010775), Yy1 (GSM1010794), Sin3a (GSM1010882), Taf1 (GSM1010812), P300 (GSM1010827), Creb1 (GSM1010719), Ets1 (GSM1010829) and Atf3 (GSM1010789) at the regions of difference in grade one and grade three patients [42]. Here, ATF3 is linked to lung adenocarcinoma.