Alteration in apoptosis balance (enhancement or diminishment) is linked to various human diseases such as autoimmune and neurodegenerative disorders, and several types of cancers.[1] The apoptotic pathway is normally initiated by cell surface death receptors such as Fas (also called CD95/Apo1), belonging to the tumor necrosis factor (TNF) receptor family.[2–4] Apoptosis is initiated when the ectodomain of Fas binds to its conjugate ligand, FasL. The gene discussed is FAS; the disease is cancer.