Consistent with the findings in PDAC tissues, EDIL3 expression was remarkably up-regulated in all of six pancreatic cancer cell lines in relative to the nonmalignant hTERT-HPNE cells at both mRNA level (Figure 3A), protein level (Figure 3B) and secreted level (Figure 3C). The gene discussed is EDIL3; the disease is familial pancreatic carcinoma.