This scale measures the degree of advanced liver fibrosis from thecalculated score based on six variables: age, BMI, relative AST/ALT, albumin, plateletcount and presence or absence of hyperglycemia or diabetes to identify or excludeadvanced liver fibrosis, defined as stages 3 and 4 of the proposed classification byBrunt, which evaluates the fibrotic stage of the histology based on five points1,18. The gene discussed is GPT; the disease is diabetes mellitus.