Of the 19 blood analytes and 8 blood cell type HE vs. LE treatment responses measured across all 3 experimental periods of the trial (Tables 4 and 6), 6 were decreased (P ≤ 0.049; prolactin, ALT, albumin, creatine kinase, LDH, cholesterol, RBC) in HE steers, whereas 3 (ALP, AST, glucose) tended (0.10 ≥ P > 0.05). The gene discussed is PRL; the disease is hereditary elliptocytosis.