There was no difference in patient age (p = 0.465), gender (p = 0.691), distance of the tumor from the anal verge (p = 0.515), tumor size (p = 0.473), differentiation (p = 0.395), cT stage (p = 0.582), cN stage (p = 0.628), CEA level (p = 0.401), or neutrophil to lymphocyte ratio (NLR) level (p = 0.650) between pCR and cCR patients. This evidence concerns the gene CEACAM5 and neoplasm.