In other studies, patients with depression showed increased serum levels of IL-1β, IL-6, IL-8, IL-12 and TNF-α, together with a decrease in IL-10 levels, an anti-inflammatory cytokine (Schiepers et al., 2005; O’Brien et al., 2007; Song et al., 2009). The gene discussed is IL1B; the disease is depressive disorder.