NRG1 and schizophrenia: Many studies using mouse models of NRG1 and ErbB4 have shown schizophrenia-related behaviors that can be reversed using antipsychotic drugs (Stefansson et al., 2002; Golub et al., 2004; O’Tuathaigh et al., 2007; Chen et al., 2008, 2010; Mei and Xiong, 2008; Shamir et al., 2012).