Given the proposed roles of SNAP23 in muscle glucose uptake, LD fusion, and channeling of FA released by LD into mitochondria for β‐oxidation, this protein seems to play an important role in the mechanisms that lead to impaired glucose uptake, impaired intramuscular lipid metabolism, and insulin resistance/type 2 diabetes (Sollner 2007; Bostrom et al. Here, SNAP23 is linked to Insulin resistance.