To summarize, analysis of the predicted target pathways of the miRNAs under investigation and ones modified by transfection with miR‐576‐5p mimics suggested alterations some of which may promote the progression of NAFLD (e.g., suppression “PPARα/RXRα activation” and “PI3K/AKT signaling”), whereas others may rather protect the liver from the pathogenic processes associated with this disease (e.g., suppression of “NF‐κB activation by viruses,” “IL‐8 signaling,” and “Production of nitric oxide and ROS in macrophages”). Here, PPARA is linked to metabolic dysfunction-associated steatotic liver disease.