Strikingly, CBPΔCH1/ΔCH1 mice exhibit stereotyped forelimb movements (Fig 2A and 2B; H (2) = 18.29, p = 0.0001; S1 Video (CBP+/+ mouse) and S2 Video (CBPΔCH1/ΔCH1 mouse)), an autism-relevant repetitive behavior [2]. The gene discussed is CREBBP; the disease is autism.