Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a systematic condition defined by three components: (1) extra skeletal calcifications; (2) abnormal metabolism of serum calcium, phosphorus, parathyroid hormone (PTH), and vitamin D; and (3) abnormal bone metabolism, including bone turnover, mineralization, linear growth, and reduced strength [1]. Here, PTH is linked to Marchiafava-Bignami disease.