The interaction between endogenous c-MYC and BPTF was validated in MIA PaCa-2 pancreas cancer cells, expressing high levels of both proteins, using the in situ proximity ligation assay (isPLA) and affinity-purified rabbit antibodies recognizing BPTF residues 913–942 (Fig. 1g; Supplementary Fig. 2a,b). Here, BPTF is linked to pancreatic neoplasm.