ACTA1 and Cirrhosis: In contrast to observation by Xia and coworkers in BDL-mouse model [117], however, no co-expression of α-SMA (the well accepted hepatic myofibroblast marker) and CK19 was observed in reacting bile duct cells and HPCs in TAA-induced rat cirrhosis; furthermore, there was no cadherin switch (from E-cadherin to N-cadherin) in these ductular cells with progressive cirrhosis.