FADD and amyotrophic lateral sclerosis: There was a 1.5-, 1.3-, and 1.8-fold increase in the level of p-FADD, although there was no statistical significance, while there was a 15.4%, 34.2%, and 36.9% decrease in the expression level of FADD, when cells were incubated in ALS at 0.1, 1, and 5 μM for 48 h, respectively, compared to the control cells (Figure 5B and Figure S5B).