EIF4E and cancer: Overexpression of eIF4E triggers neoplastic growth largely by initiating the translation of many oncogenic proteins such as c-FLIP, cyclin D1, MMPs, VEGF, c-Myc, HIF1α and ornithine decarboxylase, thereby, facilitating the cancer cells to over-ride the normal growth constrains to invade and maintain the necessary signaling pathways to favour metastatic cascades4.