Mice of group rSjcystatin-TNBS developed severe inflammation as TNBS-induced colitis of mice at the level of MPO (0.92 ± 0.28 vs 1.45 ± 0.52) U/g, MAO (7.14 ± 0.69 vs 7.83 ± 0.98) and MIO (5.17 ± 0.75 vs 6.17 ± 1.72) 3 days afterwards (Fig. 1). The gene discussed is MPO; the disease is colitis.