Intriguingly, the aberrant expression of Bcl6 has been implicated in some of virus-associated diseases such as Epstein-Barr virus (EBV)-positive Burkitt lymphoma and hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), suggesting a potential role for Bcl6 in viral control16, 17, 18. Here, BCL6 is linked to Burkitt lymphoma.