We first performed 3C experiments on the IGROV-1 ovarian cancer cell line expressing high levels of PTPN6 and miR-200c/141 transcripts (Fig. 8c,d; see Supplementary Fig. 1d and Supplementary Fig. 6c for comparative quantification of PTPN6 and miR-200c-141 primary transcripts in IGROV-1 and SKOV3 cell lines). The gene discussed is PTPN6; the disease is ovarian cancer.