IL10 and colitis: Fp strain A2-165 has been shown to attenuate colitis induced by 2,4,6-trinitrobenzenesulfonic acid (TNBS) or dinitrobenzenesulfonic acid (DNBS) in mice and to induce a relatively high IL-10 to IL-12p70 cytokine ratio in human peripheral blood mononuclear cells (hPBMCs)14, 16.