TNF and neoplasm: In a final series of studies to clarify the potential role of the cytokine changes observed in the tumor models, and specifically the role they may play in tumor metastasis, we studied the effect of Anti‐IL‐6, anti‐IL‐17, and anti‐TNFα on metastasis of 4THM tumors (Fig. 6A), and on the 4THM exosome induced enhanced metastasis of EMT6 tumors in WT mice (Fig. 6B).