In line with the concept of stabilizing E-cadherin junctions via Src inhibition, we isolated metastatic tumor cells that had colonized the liver of invasive Pdx1-Cre; KrasG12D; p53R172H; E-cadherin-GFP mice using whole-body fluorescence imaging (Figures 7A and 7B, whole-body imaging and inset, respectively, showing primary tumor and liver micro-metastases isolated from the same mouse). This evidence concerns the gene SRC and neoplasm.