TP53 and pancreatic ductal adenocarcinoma: Using these cells, we generated stable pancreatic ductal adenocarcinoma (PDAC) p53−/− cells expressing empty vector alone (p53−/− vector) or the human equivalent of murine p53R172H (p53−/− R175H) with E-cadherin-GFP (Muller et al., 2013, Tan et al., 2014).