CDH1 and neoplasm: Our capacity to isolate and image micro-metastases in the liver illustrates the power of this model for assessing subcellular changes in E-cadherin dynamics at secondary tumor sites that retain E-cadherin expression and may take advantage of this existing pool of E-cadherin during the early stages of mesenchymal-to-epithelial transition (MET) and tumor colonization (Lamouille et al., 2014, Ocaña et al., 2012).