A 72-h cell proliferation assay for MMRi6 showed IC50s of ~0.5 μM and ~3 μM in wt-p53 and p53-null Emu-myc lymphoma cells, respectively, indicating that p53 contributes to a ~6-fold difference in MMRi6 sensitivity in this set of mouse lymphoma cells (Figure 6a, data from two doses were shown). This evidence concerns the gene TP53 and lymphoma.