SOD1 and ischemia: Sedaghat et al. reported a significant increase in CAT and SOD activity 24 hours after 45 minutes of unilateral renal ischemia in Sprague-Dawley rats that was associated with four cycles of 5 minutes of ischemia and 5 minutes of reperfusion (rIPerC) on the left femoral artery (compared to the IR group) [69].