CRP and Sepsis: It is well known that an increased level of CRP, the most widely used marker of sepsis in NICU, is not necessarily diagnostic for sepsis, as elevations may also occur due to the physiologic rise after birth or non-infectious conditions, such as maternal fever during labor, PROM, vaginal delivery, fetal distress, perinatal asphyxia, meconium aspiration, respiratory distress syndrome, and surfactant administration [6–8].