Supporting this, Dynlacht and colleagues demonstrated that depletion of Nek2, a proto-oncogene that is highly expressed in various cancer types, or of Kif24 could rescue ciliogenesis and thereby restrict proliferation in breast cancer cells, although there is no impact of deletion in a most invasive cell line possibly due to the accumulation of genetic alterations [35]. The gene discussed is NEK2; the disease is breast carcinoma.