TP63 and breast cancer: For example, down-regulation of miR-451 can promote breast cancer cell survival and endocrine resistance [8], a miRNA196a2-TP63 circuit controls breast cancer proliferation and invasiveness properties [9], loss of miR-200c promotes breast cancer cell migration and invasion [10], and down-regulation of miR-29 contributes to progestin-induced stem cell expansion [11].