Specifically, a dramatically higher number of cases of PTC without CCDC67 mRNA expression displayed high TNM stages III/IV, pathological grade II, and lymph node metastasis, with χ2 = 8.236, 4.236, and 4.322, respectively, and P < 0.05 in all cases. The gene discussed is DEUP1; the disease is metastatic malignant neoplasm in the lymph nodes.