Although there are several cell lines harboring NTRK fusion, including CUTO-3 lung cancer cells with MPRIP-NTRK1 fusion and MO-91 acute myeloid leukemia (AML) cells with ETV6-NTRK3 fusion, KM12 is the only available colon cancer cell line harboring NTRK1 fusion. Here, NTRK1 is linked to malignant colon neoplasm.