On the univariate Cox proportional hazards analysis, factors associated with mortality included the NLR, albumin, alanine aminotransferase, blood glucose, ascites, AST, alkaline phosphatase (AKP), γ-glutamyl transferase (γ-GT), PT, PTA, AFP, white blood cell, platelet, number of nodules, greatest tumor diameter, MVI, portal vein thrombosis, CTP score and CLIP score (all P < 0.05). The gene discussed is AFP; the disease is neoplasm.