VDAC1 and cancer: In the SiHa and CaSki cervical cancer cells in which the VDAC1 gene had been silenced, the presence of JC-1 monomer in the cytoplasm, as detected by green fluorescence (white arrow in Figure 4A), meant a low MMP in the cervical cancer cells, and the presence of J-aggregates, as exhibited by red fluorescence in the mitochondria, indicated living cancer cells.