When the data from the WT mice were segregated according to viral titers, we found that WT mice that had not controlled LCMV-clone 13 infection at this time point, appeared as outliers and had proportions and numbers of T-bet+ Eomes- virus-specific CD8+ T cells comparable to Irf4+/fl mice (Fig 6B and 6E). This evidence concerns the gene IRF4 and infection.