Despite these reports, the role of each FGFR2 isoform in carcinomas remains controversial: FGFR2b has been identified as the FGFR2 isoform possibly involved in SCC anchorage-independent growth [45] and FGFR2c may act as a possible driver of mesenchymal-epithelial transition (MET) during metastatic cascade [15]. Here, FGFR2 is linked to carcinoma.