Interestingly, FGFR2 depletion appeared to induce a significant increase of Snail1 mRNA in HaCaT pBp-FGFR2b cells (Figure 6e), suggesting that, consistent with its tumor suppressive role, FGFR2b would exert a repressive role on this master inductor of EMT. This evidence concerns the gene FGFR2 and neoplasm.