BCL2 and acute lymphoblastic leukemia: It has been reported that the BCL-2/BCL-XL inhibitors ABT-737, ABT-263, and ABT-199 induce rapid and robust apoptosis in ALL cells, both in vitro (Alford et al., 2015, Del Gaizo Moore et al., 2008, High et al., 2010) and in human-derived xenografts (Suryani et al., 2014).