For ETV6‐RUNX1‐positive leukemia, the translocation of chromosomes 12 and 21 is one of the best targets to monitor MRD and is an accurate measurement of ETV6‐RUNX1 transcripts by quantitative real‐time polymerase chain reaction (Q‐PCR) 37, 38, 39, 40. The gene discussed is RUNX1; the disease is leukemia.